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Mecolagin 0.5mg Chewable Tablet 10pcs
Mecobalamin, the neurologically active form of vitamin B12, is a water-soluble vitamin in the body. It serves as a cofactor in methionine synthase, aiding in the transfer of methyl groups to regenerate methionine from homocysteine. In anemia, it enhances erythrocyte production by promoting nucleic acid synthesis in the bone marrow and facilitating the maturation and division of erythrocytes.
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✅ Description:
Mecolagin 0.5 contains Mecobalamin which belongs to the group of medicines called Vitamins. Mecolagin 0.5 is used to manage peripheral neuropathies (peripheral nerve damage that affects hands, feet, and arms) and megaloblastic anemia (a blood disorder that occurs due to abnormal production of red blood cells) caused by vitamin B12 deficiency in affected individuals.
Mecolagin 0.5 is not recommended for use in patients allergic to mecobalamin and/or other B12-containing medicines. It is also not recommended for use in patients with Leber’s disease (an inherited form of vision loss).
Before taking Mecolagin 0.5, inform your doctor if you are in an occupation of handling mercury and/or have kidney problems (such as renal failure) and liver problems (such as hepatic impairment).
Mecolagin 0.5 is not recommended for use during pregnancy and in breastfeeding women. It should be used with caution in children and adolescents (aged 6 months to 18 years). It is also used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
Safety Advices
Alcohol
UNSAFE
If you consume alcohol in excess regularly, your doctor may monitor your vitamin B12 levels to check the progress of treatment.
Pregnancy
CONSULT YOUR DOCTOR
Mecolagin 0.5 is not recommended for use in pregnant women. Consult your doctor before taking Mecolagin 0.5.
Breastfeeding
CONSULT YOUR DOCTOR
Mecolagin 0.5 is not recommended for use in breastfeeding women. Consult your doctor before taking Mecolagin 0.5.
Driving
CAUTION
Mecobalamin Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Mecolagin 0.5 should be used with caution in patients with kidney problems such as renal failure. Consult your doctor before taking the medicine.
Liver
CONSULT YOUR DOCTOR
Mecolagin 0.5 should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking the medicine.
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✔️ Uses of Mecolagin 0.5
- Megaloblastic anemia
- Peripheral neuropathies
✔️ How does Mecolagin 0.5 work?
Mecolagin 0.5 is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anemias and nerve problems.
✔️ Side Effects of Mecolagin 0.5
Dermatologic Effects:
- Rash (discontinue treatment if this occurs)
Gastrointestinal Effects:
- Anorexia, nausea, vomiting, and diarrhea
Neurologic Effects (Central Nervous System):
- Headache
Others:
- Anaphylactoid reactions (e.g., decreased blood pressure or dyspnea)
- Hot sensation
- Diaphoresis
- Pain
✔️ Benefits of Mecolagin 0.5
- Mecolagin 0.5 is a form of vitamin B12 that helps in the formation of nerve cells and the regeneration of damaged nerves in the brain.
- It also plays an important role in red blood cell formation and DNA synthesis.
- It also plays a major role in protein and fat metabolism, fertility, and the functioning of various hormones.
✔️ Mecolagin Tablet is indicated for:
- Peripheral neuropathy
- Diabetic neuropathy
- Alcoholic neuropathy
- Drug-induced neuropathy
- Entrapment neuropathy
- Lumbago
- Intercostal neuralgia
- Diabetic retinopathy
- Multiple sclerosis
- Vertebral syndrome
- Parkinson's disease
- Alzheimer's disease
- Bell's palsy
✔️ Pharmacology
Mecobalamin, a coenzyme form of vitamin B12, replaces the cyano group in cyanocobalamin with a methyl group. It acts as a cofactor in methionine synthase, which is essential for transferring methyl groups to regenerate methionine from homocysteine. Mecobalamin is crucial for myelin integrity, neuronal function, red blood cell formation, and DNA synthesis. It aids in neuronal lipid synthesis, and axonal nerve regeneration, promotes axonal transport, and possesses neuroprotective properties.
✔️ Dosage & Administration of Mecolagin 0.5
Tablet:
- 0.5 mg tablet taken three times daily after meals.
- Dosage adjustments may be necessary based on age and symptom severity.
✔️ Interaction
- Absorption of vitamin B12 may be reduced by neomycin, aminosalicylic acid, H2-antagonists, omeprazole, and colchicine.
- Serum concentrations may be decreased by oral contraceptives.
- These interactions may not be clinically significant but should be considered during blood concentration assays.
✔️ Contraindications
Hypersensitivity to Mecobalamin or any formulation components.
✔️ Pregnancy & Lactation
- No data is available on Mecobalamin use in pregnant women and lactating mothers.
- Vitamin B12 is distributed in breast milk and is generally considered compatible with breastfeeding by the American Academy of Pediatrics.
✔️ Precautions & Warnings
- Mecolagin should not be used aimlessly for more than one month unless effective.
- Prolonged use of larger doses is not recommended for patients handling mercury or mercury compounds.
✔️ Storage:
- Store at room temperature.
- Protect from moisture and light.
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